Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)2. The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FTIR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of Ag+-doped fluorapatite particles which may lead to their death.... The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry.
TY - JOUR
AU - Stanić, Vojislav
AU - Radosavljević-Mihajlović, Ana
AU - Živković-Radovanović, Vukosava
AU - Nastasijević, Branislav
AU - Marković, Jelena
AU - Budimir, Milica
PY - 2015
UR - https://ritnms.itnms.ac.rs/handle/123456789/998
AB - Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)2. The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FTIR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of Ag+-doped fluorapatite particles which may lead to their death. The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry.
PB - Elsevier B.V.
T2 - Applied Surface Science
T1 - Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method
EP - 80
IS - 15
SP - 72
VL - 337
DO - 10.1016/j.apsusc.2015.02.065
ER -
@article{
author = "Stanić, Vojislav and Radosavljević-Mihajlović, Ana and Živković-Radovanović, Vukosava and Nastasijević, Branislav and Marković, Jelena and Budimir, Milica",
year = "2015",
abstract = "Silver doped fluorapatite nanopowders were synthesised by neutralization method, which consists of dissolving Ag2O in solution of HF and H3PO4 and addition to suspension of Ca(OH)2. The powder XRD, SEM and FTIR studies indicated the formation of a fluorapatite nanomaterials with average length of the particles is about 80 nm and a width of about 15 nm. The FTIR studies show that carbonate content in samples is very small and carbonte ions substitute both phosphate and hydroxyl groups in the crystal structure of samples, forming AB-type fluorapatite. Antibacterial studies have demonstrated that all Ag+-doped fluorapatite samples exhibit bactericidal effect against pathogens: Staphylococcus aureus, Micrococcus luteus and Kllebsiela pneumoniae. Antibacterial activity increased with the increase of Ag+ in the samples. The atomic force microscopy studies revealed extensive damage to the bacterial cell envelops in the presence of Ag+-doped fluorapatite particles which may lead to their death. The synthesized Ag+-doped fluorapatite nanomaterials are promising as antibacterial biomaterials in orthopedics and dentistry.",
publisher = "Elsevier B.V.",
journal = "Applied Surface Science",
title = "Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method",
pages = "80-72",
number = "15",
volume = "337",
doi = "10.1016/j.apsusc.2015.02.065"
}
Stanić, V., Radosavljević-Mihajlović, A., Živković-Radovanović, V., Nastasijević, B., Marković, J.,& Budimir, M.. (2015). Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method. in Applied Surface Science
Elsevier B.V.., 337(15), 72-80.
https://doi.org/10.1016/j.apsusc.2015.02.065
Stanić V, Radosavljević-Mihajlović A, Živković-Radovanović V, Nastasijević B, Marković J, Budimir M. Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method. in Applied Surface Science. 2015;337(15):72-80.
doi:10.1016/j.apsusc.2015.02.065 .
Stanić, Vojislav, Radosavljević-Mihajlović, Ana, Živković-Radovanović, Vukosava, Nastasijević, Branislav, Marković, Jelena, Budimir, Milica, "Synthesis, structural characterisation and antibacterial activity of Ag+-doped fluorapatite nanomaterials prepared by neutralization method" in Applied Surface Science, 337, no. 15 (2015):72-80,
https://doi.org/10.1016/j.apsusc.2015.02.065 . .
