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Characterization of different bioactive phosphate glasses

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2019
ACA-VIII-Topalovic-repozitorijum.pdf (647.7Kb)
Authors
Topalović, Vladimir
Matijašević, Srđan
Nikolić, Jelena
Đošić, Marija
Savić, Veljko
Smiljanić, Sonja
Grujić, Snežana
Contributors
Mitić, Vojislav
Mančić, Lidija
Obradović, Nina
Conference object (Published version)
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Abstract
Due to their potential bioactive properties, different types of phosphate based glasses have been considered for bone tissue engineering and drug delivery applications. In this experiment, four different compositions of glasses (42P2O5·40CaO·5SrO·10Na2O·3TiO2 , 46P2O5·40CaO·SrO·10Na2O·3TiO2 , 42P2O5·40CaO·5La2O3·10Na2O·3TiO2 , and 46P2O5·40CaO·La2O3·10Na2O·3TiO2 (mol%)) were obtained by standard melt-quenching method. The crystallization and sintering behavior of glasses have been studied by using DTA, HSM and XRD methods. For all of the glass compositions the sintered phosphate glass-ceramic samples contained certain bioactive phases (α-Ca3(PO4)2, β-Ca3(PO4)2, β-Ca2P2O7,β-CaP2O6). Based on the glass properties, the use of these glasses in obtaining the bioactive glass scaffolds with a suitable interconnected porous structure is achievable. Bioactive scaffolds have potential to aid the bone regeneration process by giving cell a temporary template to grow into, provoking bone cell activ...ity. Also, glasses with stable uniform porous structure and high surface area can be used as porous carriers for controlled drug delivery.

Source:
ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing, 2019, 60-60
Publisher:
  • Belgrade : Serbian Ceramic Society
Funding / projects:
  • The development of glasses with controlled ions release for application in agriculture and medicine (RS-34001)
  • Phenomena and processes of the synthesis of new glassy and nano-structured glass-ceramics materials (RS-172004)

ISBN: 978-86-915627-7-9

[ Google Scholar ]
URI
https://ritnms.itnms.ac.rs/handle/123456789/803
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Institut za tehnologiju nuklearnih i drugih mineralnih sirovina
TY  - CONF
AU  - Topalović, Vladimir
AU  - Matijašević, Srđan
AU  - Nikolić, Jelena
AU  - Đošić, Marija
AU  - Savić, Veljko
AU  - Smiljanić, Sonja
AU  - Grujić, Snežana
PY  - 2019
UR  - https://ritnms.itnms.ac.rs/handle/123456789/803
AB  - Due to their potential bioactive properties, different types of phosphate based glasses have been considered for bone tissue engineering and drug delivery applications. In this experiment, four different compositions of glasses (42P2O5·40CaO·5SrO·10Na2O·3TiO2 , 46P2O5·40CaO·SrO·10Na2O·3TiO2 , 42P2O5·40CaO·5La2O3·10Na2O·3TiO2 , and 46P2O5·40CaO·La2O3·10Na2O·3TiO2 (mol%)) were obtained by standard melt-quenching method. The crystallization and sintering behavior of glasses have been studied by using DTA, HSM and XRD methods. For all of the glass compositions the sintered phosphate glass-ceramic samples contained certain bioactive phases (α-Ca3(PO4)2, β-Ca3(PO4)2, β-Ca2P2O7,β-CaP2O6). Based on the glass properties, the use of these glasses in obtaining the bioactive glass scaffolds with a suitable interconnected porous structure is achievable. Bioactive scaffolds have potential to aid the bone regeneration process by giving cell a temporary template to grow into, provoking bone cell activity. Also, glasses with stable uniform porous structure and high surface area can be used as porous carriers for controlled drug delivery.
PB  - Belgrade : Serbian Ceramic Society
C3  - ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing
T1  - Characterization of different bioactive phosphate glasses
EP  - 60
SP  - 60
ER  - 
@conference{
author = "Topalović, Vladimir and Matijašević, Srđan and Nikolić, Jelena and Đošić, Marija and Savić, Veljko and Smiljanić, Sonja and Grujić, Snežana",
year = "2019",
abstract = "Due to their potential bioactive properties, different types of phosphate based glasses have been considered for bone tissue engineering and drug delivery applications. In this experiment, four different compositions of glasses (42P2O5·40CaO·5SrO·10Na2O·3TiO2 , 46P2O5·40CaO·SrO·10Na2O·3TiO2 , 42P2O5·40CaO·5La2O3·10Na2O·3TiO2 , and 46P2O5·40CaO·La2O3·10Na2O·3TiO2 (mol%)) were obtained by standard melt-quenching method. The crystallization and sintering behavior of glasses have been studied by using DTA, HSM and XRD methods. For all of the glass compositions the sintered phosphate glass-ceramic samples contained certain bioactive phases (α-Ca3(PO4)2, β-Ca3(PO4)2, β-Ca2P2O7,β-CaP2O6). Based on the glass properties, the use of these glasses in obtaining the bioactive glass scaffolds with a suitable interconnected porous structure is achievable. Bioactive scaffolds have potential to aid the bone regeneration process by giving cell a temporary template to grow into, provoking bone cell activity. Also, glasses with stable uniform porous structure and high surface area can be used as porous carriers for controlled drug delivery.",
publisher = "Belgrade : Serbian Ceramic Society",
journal = "ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing",
title = "Characterization of different bioactive phosphate glasses",
pages = "60-60"
}
Topalović, V., Matijašević, S., Nikolić, J., Đošić, M., Savić, V., Smiljanić, S.,& Grujić, S.. (2019). Characterization of different bioactive phosphate glasses. in ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing
Belgrade : Serbian Ceramic Society., 60-60.
Topalović V, Matijašević S, Nikolić J, Đošić M, Savić V, Smiljanić S, Grujić S. Characterization of different bioactive phosphate glasses. in ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing. 2019;:60-60..
Topalović, Vladimir, Matijašević, Srđan, Nikolić, Jelena, Đošić, Marija, Savić, Veljko, Smiljanić, Sonja, Grujić, Snežana, "Characterization of different bioactive phosphate glasses" in ADVANCED CERAMICS AND APPLICATION VIII New Frontiers in Multifunctional Material Science and Processing (2019):60-60.

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