In the last two decades, natural zeolites have emerged in biomedical applications due to their favorable physicochemical characteristics such as high adsorption capacity and specific surface, the cation exchange ability, and good biocompatibility. Although very similar to clays that have been traditionally used in pharmaceutical preparations, these mineral materials also require a comprehensive characterization prior to their use as potential pharmaceutical excipients, that is, drug carriers. In this chapter a brief summary on definitions, properties, functionality-related characteristics, safety, and regulatory aspects of pharmaceutical excipients is given. Special attention is focused on natural and surfactant-modified zeolites; an overview of techniques used for characterization of a starting mineral material as well as drug-modified zeolite composites relevant for their application as pharmaceutical excipients and potential drug carriers is presented.
TY - CHAP
AU - Krajišnik, Danina
AU - Daković, Aleksandra
AU - Milić, Jela
AU - Marković, Marija
PY - 2018
UR - https://ritnms.itnms.ac.rs/handle/123456789/465
AB - In the last two decades, natural zeolites have emerged in biomedical applications due to their favorable physicochemical characteristics such as high adsorption capacity and specific surface, the cation exchange ability, and good biocompatibility. Although very similar to clays that have been traditionally used in pharmaceutical preparations, these mineral materials also require a comprehensive characterization prior to their use as potential pharmaceutical excipients, that is, drug carriers. In this chapter a brief summary on definitions, properties, functionality-related characteristics, safety, and regulatory aspects of pharmaceutical excipients is given. Special attention is focused on natural and surfactant-modified zeolites; an overview of techniques used for characterization of a starting mineral material as well as drug-modified zeolite composites relevant for their application as pharmaceutical excipients and potential drug carriers is presented.
PB - Elsevier
T2 - Modified Clay and Zeolite Nanocomposite Materials: Environmental and Pharmaceutical Applications
T1 - Zeolites as potential drug carriers
EP - 55
SP - 27
DO - 10.1016/B978-0-12-814617-0.00002-5
UR - conv_1027
ER -
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author = "Krajišnik, Danina and Daković, Aleksandra and Milić, Jela and Marković, Marija",
year = "2018",
abstract = "In the last two decades, natural zeolites have emerged in biomedical applications due to their favorable physicochemical characteristics such as high adsorption capacity and specific surface, the cation exchange ability, and good biocompatibility. Although very similar to clays that have been traditionally used in pharmaceutical preparations, these mineral materials also require a comprehensive characterization prior to their use as potential pharmaceutical excipients, that is, drug carriers. In this chapter a brief summary on definitions, properties, functionality-related characteristics, safety, and regulatory aspects of pharmaceutical excipients is given. Special attention is focused on natural and surfactant-modified zeolites; an overview of techniques used for characterization of a starting mineral material as well as drug-modified zeolite composites relevant for their application as pharmaceutical excipients and potential drug carriers is presented.",
publisher = "Elsevier",
journal = "Modified Clay and Zeolite Nanocomposite Materials: Environmental and Pharmaceutical Applications",
booktitle = "Zeolites as potential drug carriers",
pages = "55-27",
doi = "10.1016/B978-0-12-814617-0.00002-5",
url = "conv_1027"
}
Krajišnik, D., Daković, A., Milić, J.,& Marković, M.. (2018). Zeolites as potential drug carriers. in Modified Clay and Zeolite Nanocomposite Materials: Environmental and Pharmaceutical Applications
Elsevier., 27-55.
https://doi.org/10.1016/B978-0-12-814617-0.00002-5
conv_1027
Krajišnik D, Daković A, Milić J, Marković M. Zeolites as potential drug carriers. in Modified Clay and Zeolite Nanocomposite Materials: Environmental and Pharmaceutical Applications. 2018;:27-55.
doi:10.1016/B978-0-12-814617-0.00002-5
conv_1027 .
Krajišnik, Danina, Daković, Aleksandra, Milić, Jela, Marković, Marija, "Zeolites as potential drug carriers" in Modified Clay and Zeolite Nanocomposite Materials: Environmental and Pharmaceutical Applications (2018):27-55,
https://doi.org/10.1016/B978-0-12-814617-0.00002-5 .,
conv_1027 .
