Natural and Modified Silica-Based Materials as Carriers for NSAIDs
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In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharm...aceutical performances.
Ključne reči:
Zeolites / Nonsteroidal anti-inflammatory drugs / Modified aluminosilicates / Excipients / Drug delivery/carriers / Diatomites / Clays / AluminosilicatesIzvor:
Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits, 2017, 219-258Izdavač:
- Elsevier Inc.
Institucija/grupa
Institut za tehnologiju nuklearnih i drugih mineralnih sirovinaTY - CHAP AU - Krajišnik, Danina AU - Daković, Aleksandra AU - Janićijević, Jelena AU - Milić, Jela PY - 2017 UR - https://ritnms.itnms.ac.rs/handle/123456789/442 AB - In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharmaceutical performances. PB - Elsevier Inc. T2 - Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits T1 - Natural and Modified Silica-Based Materials as Carriers for NSAIDs EP - 258 SP - 219 DO - 10.1016/B978-0-12-804017-1.00008-X UR - conv_1031 ER -
@inbook{ author = "Krajišnik, Danina and Daković, Aleksandra and Janićijević, Jelena and Milić, Jela", year = "2017", abstract = "In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharmaceutical performances.", publisher = "Elsevier Inc.", journal = "Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits", booktitle = "Natural and Modified Silica-Based Materials as Carriers for NSAIDs", pages = "258-219", doi = "10.1016/B978-0-12-804017-1.00008-X", url = "conv_1031" }
Krajišnik, D., Daković, A., Janićijević, J.,& Milić, J.. (2017). Natural and Modified Silica-Based Materials as Carriers for NSAIDs. in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits Elsevier Inc.., 219-258. https://doi.org/10.1016/B978-0-12-804017-1.00008-X conv_1031
Krajišnik D, Daković A, Janićijević J, Milić J. Natural and Modified Silica-Based Materials as Carriers for NSAIDs. in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits. 2017;:219-258. doi:10.1016/B978-0-12-804017-1.00008-X conv_1031 .
Krajišnik, Danina, Daković, Aleksandra, Janićijević, Jelena, Milić, Jela, "Natural and Modified Silica-Based Materials as Carriers for NSAIDs" in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits (2017):219-258, https://doi.org/10.1016/B978-0-12-804017-1.00008-X ., conv_1031 .