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Natural and Modified Silica-Based Materials as Carriers for NSAIDs

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Authors
Krajišnik, Danina
Daković, Aleksandra
Janićijević, Jelena
Milić, Jela
Book part (Published version)
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Abstract
In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharm...aceutical performances.

Keywords:
Zeolites / Nonsteroidal anti-inflammatory drugs / Modified aluminosilicates / Excipients / Drug delivery/carriers / Diatomites / Clays / Aluminosilicates
Source:
Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits, 2017, 219-258
Publisher:
  • Elsevier Inc.

DOI: 10.1016/B978-0-12-804017-1.00008-X

Scopus: 2-s2.0-85022179308
[ Google Scholar ]
7
URI
https://ritnms.itnms.ac.rs/handle/123456789/442
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Institut za tehnologiju nuklearnih i drugih mineralnih sirovina
TY  - CHAP
AU  - Krajišnik, Danina
AU  - Daković, Aleksandra
AU  - Janićijević, Jelena
AU  - Milić, Jela
PY  - 2017
UR  - https://ritnms.itnms.ac.rs/handle/123456789/442
AB  - In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharmaceutical performances.
PB  - Elsevier Inc.
T2  - Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits
T1  - Natural and Modified Silica-Based Materials as Carriers for NSAIDs
EP  - 258
SP  - 219
DO  - 10.1016/B978-0-12-804017-1.00008-X
UR  - conv_1031
ER  - 
@inbook{
author = "Krajišnik, Danina and Daković, Aleksandra and Janićijević, Jelena and Milić, Jela",
year = "2017",
abstract = "In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related characteristics along with good biocompatibility. The possibility of their use in drug delivery as carriers for NSAIDs, as one of the most widely prescribed drugs, is particularly interesting since it would overcome some of the therapy-related side effects and improve patience compliance.This chapter gives an overview of natural silica-based materials' characteristics relevant for their pharmaceutical use, along with various examples of their structure modification in order to obtain materials with improved functional properties as potential drug carriers. A review on application of these materials in drug delivery of NSAIDs is presented including evaluation of techniques used for drug silica based carrier characterization in addition to investigation of their biopharmaceutical performances.",
publisher = "Elsevier Inc.",
journal = "Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits",
booktitle = "Natural and Modified Silica-Based Materials as Carriers for NSAIDs",
pages = "258-219",
doi = "10.1016/B978-0-12-804017-1.00008-X",
url = "conv_1031"
}
Krajišnik, D., Daković, A., Janićijević, J.,& Milić, J.. (2017). Natural and Modified Silica-Based Materials as Carriers for NSAIDs. in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits
Elsevier Inc.., 219-258.
https://doi.org/10.1016/B978-0-12-804017-1.00008-X
conv_1031
Krajišnik D, Daković A, Janićijević J, Milić J. Natural and Modified Silica-Based Materials as Carriers for NSAIDs. in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits. 2017;:219-258.
doi:10.1016/B978-0-12-804017-1.00008-X
conv_1031 .
Krajišnik, Danina, Daković, Aleksandra, Janićijević, Jelena, Milić, Jela, "Natural and Modified Silica-Based Materials as Carriers for NSAIDs" in Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits (2017):219-258,
https://doi.org/10.1016/B978-0-12-804017-1.00008-X .,
conv_1031 .

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