TY  - JOUR
AU  - Izzo, Francesco
AU  - Mercurio, Mariano
AU  - de Gennaro, Bruno
AU  - Aprea, Paolo
AU  - Cappelletti, Piergiulio
AU  - Daković, Aleksandra
AU  - Germinario, Chiara
AU  - Grifa, Celestino
AU  - Smiljanić, Danijela
AU  - Langella, Alessio
PY  - 2019
UR  - https://ritnms.itnms.ac.rs/handle/123456789/496
AB  - The present research deals with the evaluation of a clinoptilolite-rich rock, occurring in the Nizny Hrabovec deposit (Slovakia), for high-value technological applications based on sorption and in vitro release of nonsteroidal anti-inflammatory drugs (i.e., ibuprofen sodium salt). This georesource was surface modified (SMNZ) using four cationic surfactants. Results demonstrate that ibuprofen sorption is very fast and SMZNs can sorb up to (similar to)26 mg/g of drug as a function of the type of counterion and morphology of surfactant, as well as the hydrophobicity and molecular structure of the drug. Maximum sorption capacities observed for all SMNZs are fully comparable to other adsorbent carriers usually used for removal of contaminants in wastewaters. Sorption of ibuprofen is controlled by a dual mechanism: external anionic exchange and partition into the hydrophobic portion of the patchy bilayer. A prompt drug release in simulated intestinal fluid (SIF) was also observed, making this natural material also suitable to provide rapid soothing effects in potential pharmacological applications. Comparing the results of this study with other recent investigations, a good technological performance of clinoptilolite-rich rock can be inferred despite the relatively low zeolite content ((similar to)56 wt.%).
PB  - Elsevier, Amsterdam
T2  - Colloids and Surfaces B-Biointerfaces
T1  - Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment
VL  - 182
DO  - 10.1016/j.colsurfb.2019.110380
UR  - conv_861
ER  - 

@article{
author = "Izzo, Francesco and Mercurio, Mariano and de Gennaro, Bruno and Aprea, Paolo and Cappelletti, Piergiulio and Daković, Aleksandra and Germinario, Chiara and Grifa, Celestino and Smiljanić, Danijela and Langella, Alessio",
year = "2019",
abstract = "The present research deals with the evaluation of a clinoptilolite-rich rock, occurring in the Nizny Hrabovec deposit (Slovakia), for high-value technological applications based on sorption and in vitro release of nonsteroidal anti-inflammatory drugs (i.e., ibuprofen sodium salt). This georesource was surface modified (SMNZ) using four cationic surfactants. Results demonstrate that ibuprofen sorption is very fast and SMZNs can sorb up to (similar to)26 mg/g of drug as a function of the type of counterion and morphology of surfactant, as well as the hydrophobicity and molecular structure of the drug. Maximum sorption capacities observed for all SMNZs are fully comparable to other adsorbent carriers usually used for removal of contaminants in wastewaters. Sorption of ibuprofen is controlled by a dual mechanism: external anionic exchange and partition into the hydrophobic portion of the patchy bilayer. A prompt drug release in simulated intestinal fluid (SIF) was also observed, making this natural material also suitable to provide rapid soothing effects in potential pharmacological applications. Comparing the results of this study with other recent investigations, a good technological performance of clinoptilolite-rich rock can be inferred despite the relatively low zeolite content ((similar to)56 wt.%).",
publisher = "Elsevier, Amsterdam",
journal = "Colloids and Surfaces B-Biointerfaces",
title = "Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment",
volume = "182",
doi = "10.1016/j.colsurfb.2019.110380",
url = "conv_861"
}

Izzo, F., Mercurio, M., de Gennaro, B., Aprea, P., Cappelletti, P., Daković, A., Germinario, C., Grifa, C., Smiljanić, D.,& Langella, A.. (2019). Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment. in Colloids and Surfaces B-Biointerfaces
Elsevier, Amsterdam., 182.
https://doi.org/10.1016/j.colsurfb.2019.110380
conv_861

Izzo F, Mercurio M, de Gennaro B, Aprea P, Cappelletti P, Daković A, Germinario C, Grifa C, Smiljanić D, Langella A. Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment. in Colloids and Surfaces B-Biointerfaces. 2019;182.
doi:10.1016/j.colsurfb.2019.110380
conv_861 .

Izzo, Francesco, Mercurio, Mariano, de Gennaro, Bruno, Aprea, Paolo, Cappelletti, Piergiulio, Daković, Aleksandra, Germinario, Chiara, Grifa, Celestino, Smiljanić, Danijela, Langella, Alessio, "Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment" in Colloids and Surfaces B-Biointerfaces, 182 (2019),
https://doi.org/10.1016/j.colsurfb.2019.110380 .,
conv_861 .