@conference{
author = "Ilić, Iva and Janković, Ana and Đošić, Marija and Vukašinović-Sekulić, Maja and Mišković-Stanković, Vesna",
year = "2017",
abstract = "Biocomposite ceramic coatings hydroxyapatite (HAP), silver/hydroxyapatite (Ag/HAP) and
silver/hydroxyapatite/graphene (Ag/HAP/Gr) are obtained on titanium by electrophoretic
deposition (EPD). The goal of this research was to develop multifunctional composite
coatings as a suitable strategy to improve the surface properties of metallic implants.
The deposition was performed on titanium electrodes with specific geometry suitable for
implantation in the frontal bone of rabbits for in vivo experiments. The effect of deposition
parameters on deposited mass was investigated by varying different values of constant
voltage for various deposition time. Uniform and compact HAP coatings were successfully
deposited at applied voltage of 30 V for 45 s, whereas Ag/HAP and Ag/HAP/Gr coatings
with satisfying adhesion and coverage were deposited at applied voltage of 60 V for 1 min.
Bearing in mind certain toxic effects of the nanoparticle silver, the deposition of the coating
of hydroxyapatite/chitosan/graphene (HAP/CS/Gr) of the same composition with the
addition of the antibiotic gentamicin was performed, in order to replace the silver
nanoparticles. The antimicrobial activity of the coating HAP/CS/Gr without and with
gentamicin against Staphylococcus aureus and Escherichia coli was examined by agar
diffusion test. Moreover, disc diffusion test showed improved bactericidal effect of
gentamicin-loaded composite coatings against Staphylococcus aureus and Escherichia coli
compared to control non-gentamicin-loaded coatings.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Sixteenth Young Researchers Conference – Materials Science and Engineering",
title = "Electrophoretic deposition of biocomposite ceramic coatings of hydroxyapatite and chitosan with silver and gentamicin on titanium for medical applications",
pages = "4-4"
}
