TY  - JOUR
AU  - Stojšić, D.
AU  - Stojković, Mileta
AU  - Daković, Aleksandra
AU  - Adamović, Milan
AU  - Tomašević-Čanović, Magdalena
PY  - 2004
UR  - https://ritnms.itnms.ac.rs/handle/123456789/66
AB  - Efikasnost adsorpcije zearalenona (ZEN) na mineralnom adsorbentu mikotoksina dobijenim organskom modifikacijom prirodnog zeolita (Min-Zel Plus®) je praćena u uslovima in vitro i ogledima in vivo na jagnjadima koja su dobijala hranu kontaminiranu ZEN-om. In vitro rezultati su pokazali da Min-Zel Plus® adsorbuje ZEN sa indeksom adsorpcije 90%, na pH 3, 7 i 9. Za in vivo eksperimente jagnjad su podeljena u četiri grupe, u svakoj grupi po 16 jagnjadi: I grupa - kontrolna je hranjena hranom koja ne sadrži ni ZEN ni Min-Zel Plus®, II grupa - je dobijala hanu kontaminiranu sa 8.3 mg ZEN/kg III grupa je dobijala hranu kontaminiranu sa 8.3 mgZEN/kg i 0.2% Min-a-Zel-a Plus® i IV grupa je dobijala hranu kontaminiranu sa 8.3 mg ZEN/kg i 0.5% Min-Zel-a Plus®. Rezultati analiza sadržaja ZEN u organima jagnjadi su pokazala da je za razliku od II grupe u kojoj je značajno prisutan ZEN u svim organima, u grupama III i IV, koje su dobijale i Min-Zel-a Plus® značajno je smanjen sadržaj ZEN u jetri, bubrezima i mišićima. Ipak, pri količini od 0.2% Min- Zel-a Plus® u ispitivanim organima jagnjadi prisutne su male količine zaostalog ZEN, dok pri količini od 0.5% nije detektovan ZEN u ispitivanim organima.
AB  - In vitro and in vivo studies were conducted to evaluate the efficacy of organozeolite (Min-a-Zel Plus®) to alleviate the toxic effects of zearalenone (ZEN) in lambs. Min-a-Zel Plus® was able to bind >90% of ZEN in vitro at pH 3, 7 and 9. For in vivo studies, sixty four lambs were divided in to four groups which included: I - control group - basal diet containing neither Min-a-Zel Plus® nor zearalenone; II - basal diet supplemented with 8.3 mg ZEN/kg diet; III - basal diet supplemented with 8.3 mg ZEN/kg and 0.2% Min-a-Zel Plus®; IV - basal diet supplemented with 8.3 mg ZEN/kg and 0.5% Min-a-Zel Plus®. The Min-a-Zel Plus® supplement dramatically reduced the content of ZEN in liver, kidneys and muscles. The lower amount (0.2%) reduced the content of ZEN in all samples, but ZEN was still present in the organs. Addition of 0.5% Min-a-Zel Plus® eliminated ZEN from all organs, totally. These results indicate that Min-a-Zel Plus® is effective in preventing the toxic effects of ZEN, which may be present in lamb rations.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria-Beograd
T1  - Efikasnost organozeolita u preveniranju toksičnih efekata zearalenona kod jagnjadi
T1  - Efficacy of organozeolite to ameliorate the toxic effects of zearalenone in lambs
EP  - 62
IS  - 1
SP  - 53
VL  - 54
DO  - 10.2298/AVB0401053S
UR  - conv_489
ER  - 

@article{
author = "Stojšić, D. and Stojković, Mileta and Daković, Aleksandra and Adamović, Milan and Tomašević-Čanović, Magdalena",
year = "2004",
abstract = "Efikasnost adsorpcije zearalenona (ZEN) na mineralnom adsorbentu mikotoksina dobijenim organskom modifikacijom prirodnog zeolita (Min-Zel Plus®) je praćena u uslovima in vitro i ogledima in vivo na jagnjadima koja su dobijala hranu kontaminiranu ZEN-om. In vitro rezultati su pokazali da Min-Zel Plus® adsorbuje ZEN sa indeksom adsorpcije 90%, na pH 3, 7 i 9. Za in vivo eksperimente jagnjad su podeljena u četiri grupe, u svakoj grupi po 16 jagnjadi: I grupa - kontrolna je hranjena hranom koja ne sadrži ni ZEN ni Min-Zel Plus®, II grupa - je dobijala hanu kontaminiranu sa 8.3 mg ZEN/kg III grupa je dobijala hranu kontaminiranu sa 8.3 mgZEN/kg i 0.2% Min-a-Zel-a Plus® i IV grupa je dobijala hranu kontaminiranu sa 8.3 mg ZEN/kg i 0.5% Min-Zel-a Plus®. Rezultati analiza sadržaja ZEN u organima jagnjadi su pokazala da je za razliku od II grupe u kojoj je značajno prisutan ZEN u svim organima, u grupama III i IV, koje su dobijale i Min-Zel-a Plus® značajno je smanjen sadržaj ZEN u jetri, bubrezima i mišićima. Ipak, pri količini od 0.2% Min- Zel-a Plus® u ispitivanim organima jagnjadi prisutne su male količine zaostalog ZEN, dok pri količini od 0.5% nije detektovan ZEN u ispitivanim organima., In vitro and in vivo studies were conducted to evaluate the efficacy of organozeolite (Min-a-Zel Plus®) to alleviate the toxic effects of zearalenone (ZEN) in lambs. Min-a-Zel Plus® was able to bind >90% of ZEN in vitro at pH 3, 7 and 9. For in vivo studies, sixty four lambs were divided in to four groups which included: I - control group - basal diet containing neither Min-a-Zel Plus® nor zearalenone; II - basal diet supplemented with 8.3 mg ZEN/kg diet; III - basal diet supplemented with 8.3 mg ZEN/kg and 0.2% Min-a-Zel Plus®; IV - basal diet supplemented with 8.3 mg ZEN/kg and 0.5% Min-a-Zel Plus®. The Min-a-Zel Plus® supplement dramatically reduced the content of ZEN in liver, kidneys and muscles. The lower amount (0.2%) reduced the content of ZEN in all samples, but ZEN was still present in the organs. Addition of 0.5% Min-a-Zel Plus® eliminated ZEN from all organs, totally. These results indicate that Min-a-Zel Plus® is effective in preventing the toxic effects of ZEN, which may be present in lamb rations.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria-Beograd",
title = "Efikasnost organozeolita u preveniranju toksičnih efekata zearalenona kod jagnjadi, Efficacy of organozeolite to ameliorate the toxic effects of zearalenone in lambs",
pages = "62-53",
number = "1",
volume = "54",
doi = "10.2298/AVB0401053S",
url = "conv_489"
}

Stojšić, D., Stojković, M., Daković, A., Adamović, M.,& Tomašević-Čanović, M.. (2004). Efikasnost organozeolita u preveniranju toksičnih efekata zearalenona kod jagnjadi. in Acta veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 54(1), 53-62.
https://doi.org/10.2298/AVB0401053S
conv_489

Stojšić D, Stojković M, Daković A, Adamović M, Tomašević-Čanović M. Efikasnost organozeolita u preveniranju toksičnih efekata zearalenona kod jagnjadi. in Acta veterinaria-Beograd. 2004;54(1):53-62.
doi:10.2298/AVB0401053S
conv_489 .

Stojšić, D., Stojković, Mileta, Daković, Aleksandra, Adamović, Milan, Tomašević-Čanović, Magdalena, "Efikasnost organozeolita u preveniranju toksičnih efekata zearalenona kod jagnjadi" in Acta veterinaria-Beograd, 54, no. 1 (2004):53-62,
https://doi.org/10.2298/AVB0401053S .,
conv_489 .

TY  - JOUR
AU  - Tomašević-Čanović, Magdalena
AU  - Daković, Aleksandra
AU  - Matijašević, Srđan
AU  - Radosavljević-Mihajlović, Ana
AU  - Adamović, Milan
AU  - Stojšić, D.
PY  - 2003
UR  - https://ritnms.itnms.ac.rs/handle/123456789/42
AB  - Pored visoke efikasnosti adsorpcije mikotoksina (aflatoksina, zearalenona ohratoksina Ai dr), kao i inertnosti u odnosu na vitamine, aminokiseline i mikro elemente, Minazel Plus je stabilan u opsegu kiselosti od pH 1 do pH 10. Negativni efekti pri upotrebi Minazela Plus nisu se javili ni u ogledima in vivo, što se i očekivalo obzirom na stabilnost organo kompleksa koja je utvrđena u in vitro uslovima. Količina koja se preporučuje za preventivnu primenu je 0.2 % (2 kg/toni potpune krmne smeše), odnosi se na slučaj kada su mikotoksini prisutni u hrani do koncentracije duplo veće od gornje dozvoljene granice. U slučaju veće kontaminacije hrane sa mikotoksinima tada se preporučuje dodavanje do 0.5 % (5 kg/toni). U tom slučaju ne javljaju se ni u tragovima rezidue mikotoksina u bubregu, jetri i mišićima mada su životinje (jagnjad), dobijale hranu kontaminiranu mikotoksinima.
AB  - Besides high efficiency for adsorption of mycotoxins (aflatoxins zearalenone, ochratoxin A etc) as well as inactivity for adsorption of vitamins, aminoacids and microelements, Minazel Plus is stable in the range from pH 1 to pH 10. Consumption of Minazel Plus in in vivo conditions caused no negative effects in animals. Based on the high chemical stability of organozeolite complex those results are expected. For preventive application of Minazel Plus, when diet contain mycotoxins in amounts twice that permitted, addition of 0.2% (2 g/kg feed) of Minazel Plus is recommended. However, the addition of 0.5% (5 g/kg) is recommended when diet contain much higher amounts of mycotoxins. In that case, even feed contain mycotoxins residues of mycotoxins in kidney, liver or muscles of lambs can not be found.
PB  - Institut PKB Agroekonomik, Padinska skela
T2  - Zbornik naučnih radova Instituta PKB Agroekonomik
T1  - Minazel plus - efikasni adsorbent mikotoksina
T1  - Minazel plus: The efficient adsorbent for mycotoxins
EP  - 351
IS  - 1
SP  - 343
VL  - 9
UR  - conv_214
ER  - 

@article{
author = "Tomašević-Čanović, Magdalena and Daković, Aleksandra and Matijašević, Srđan and Radosavljević-Mihajlović, Ana and Adamović, Milan and Stojšić, D.",
year = "2003",
abstract = "Pored visoke efikasnosti adsorpcije mikotoksina (aflatoksina, zearalenona ohratoksina Ai dr), kao i inertnosti u odnosu na vitamine, aminokiseline i mikro elemente, Minazel Plus je stabilan u opsegu kiselosti od pH 1 do pH 10. Negativni efekti pri upotrebi Minazela Plus nisu se javili ni u ogledima in vivo, što se i očekivalo obzirom na stabilnost organo kompleksa koja je utvrđena u in vitro uslovima. Količina koja se preporučuje za preventivnu primenu je 0.2 % (2 kg/toni potpune krmne smeše), odnosi se na slučaj kada su mikotoksini prisutni u hrani do koncentracije duplo veće od gornje dozvoljene granice. U slučaju veće kontaminacije hrane sa mikotoksinima tada se preporučuje dodavanje do 0.5 % (5 kg/toni). U tom slučaju ne javljaju se ni u tragovima rezidue mikotoksina u bubregu, jetri i mišićima mada su životinje (jagnjad), dobijale hranu kontaminiranu mikotoksinima., Besides high efficiency for adsorption of mycotoxins (aflatoxins zearalenone, ochratoxin A etc) as well as inactivity for adsorption of vitamins, aminoacids and microelements, Minazel Plus is stable in the range from pH 1 to pH 10. Consumption of Minazel Plus in in vivo conditions caused no negative effects in animals. Based on the high chemical stability of organozeolite complex those results are expected. For preventive application of Minazel Plus, when diet contain mycotoxins in amounts twice that permitted, addition of 0.2% (2 g/kg feed) of Minazel Plus is recommended. However, the addition of 0.5% (5 g/kg) is recommended when diet contain much higher amounts of mycotoxins. In that case, even feed contain mycotoxins residues of mycotoxins in kidney, liver or muscles of lambs can not be found.",
publisher = "Institut PKB Agroekonomik, Padinska skela",
journal = "Zbornik naučnih radova Instituta PKB Agroekonomik",
title = "Minazel plus - efikasni adsorbent mikotoksina, Minazel plus: The efficient adsorbent for mycotoxins",
pages = "351-343",
number = "1",
volume = "9",
url = "conv_214"
}

Tomašević-Čanović, M., Daković, A., Matijašević, S., Radosavljević-Mihajlović, A., Adamović, M.,& Stojšić, D.. (2003). Minazel plus - efikasni adsorbent mikotoksina. in Zbornik naučnih radova Instituta PKB Agroekonomik
Institut PKB Agroekonomik, Padinska skela., 9(1), 343-351.
conv_214

Tomašević-Čanović M, Daković A, Matijašević S, Radosavljević-Mihajlović A, Adamović M, Stojšić D. Minazel plus - efikasni adsorbent mikotoksina. in Zbornik naučnih radova Instituta PKB Agroekonomik. 2003;9(1):343-351.
conv_214 .

Tomašević-Čanović, Magdalena, Daković, Aleksandra, Matijašević, Srđan, Radosavljević-Mihajlović, Ana, Adamović, Milan, Stojšić, D., "Minazel plus - efikasni adsorbent mikotoksina" in Zbornik naučnih radova Instituta PKB Agroekonomik, 9, no. 1 (2003):343-351,
conv_214 .