Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin
Authors
Stevanović, MilenaĐošić, Marija
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Janković, Ana
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Mišković-Stanković, Vesna
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Contributors
Srdić, VladimirConference object (Published version)
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Metadata
Show full item recordAbstract
Hydroxyapatite (HAP) is a widely used biochemical material, because it promotes
osteointegration, has outstanding biocompatibility and chemical composition similar to
natural bone. In order to improve the mechanical and antimicrobial properties of HAP,
biocompatible, natural polymer chitosan and antibiotic gentamicin were employed. The
obtained composite hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) was assembled
on pure Ti plates using the cathodic electrophoretic deposition process from an aqueous
suspension.
The aim was to produce a uniform bioactive coating with improved mechanical
strength and favorable antibacterial properties. HAP/CS/Gent coatings were
characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR),
X-ray photoelectron spectroscopy (XPS), field emission scanning electron
microscopy (FE-SEM). Addition of the polymer significantly improved morphology, and
bioactivity of thus formed composite. HAP/CS/Gent composite coatings e...xhibited strong
antibacterial activity against Staphylococcus aureus and Escherichia coli.
Source:
12th Conference for Young Scientists in Ceramics, CYSC-2017, 2017, 93-93Publisher:
- Novi Sad : University of Novi Sad, Faculty of Technology
Funding / projects:
- Synthesis, processing and applications of nanostructured multifunctional materials with defined properties (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
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Institution/Community
Institut za tehnologiju nuklearnih i drugih mineralnih sirovinaTY - CONF AU - Stevanović, Milena AU - Đošić, Marija AU - Janković, Ana AU - Mišković-Stanković, Vesna PY - 2017 UR - https://ritnms.itnms.ac.rs/handle/123456789/776 AB - Hydroxyapatite (HAP) is a widely used biochemical material, because it promotes osteointegration, has outstanding biocompatibility and chemical composition similar to natural bone. In order to improve the mechanical and antimicrobial properties of HAP, biocompatible, natural polymer chitosan and antibiotic gentamicin were employed. The obtained composite hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) was assembled on pure Ti plates using the cathodic electrophoretic deposition process from an aqueous suspension. The aim was to produce a uniform bioactive coating with improved mechanical strength and favorable antibacterial properties. HAP/CS/Gent coatings were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FE-SEM). Addition of the polymer significantly improved morphology, and bioactivity of thus formed composite. HAP/CS/Gent composite coatings exhibited strong antibacterial activity against Staphylococcus aureus and Escherichia coli. PB - Novi Sad : University of Novi Sad, Faculty of Technology C3 - 12th Conference for Young Scientists in Ceramics, CYSC-2017 T1 - Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin EP - 93 SP - 93 ER -
@conference{ author = "Stevanović, Milena and Đošić, Marija and Janković, Ana and Mišković-Stanković, Vesna", year = "2017", abstract = "Hydroxyapatite (HAP) is a widely used biochemical material, because it promotes osteointegration, has outstanding biocompatibility and chemical composition similar to natural bone. In order to improve the mechanical and antimicrobial properties of HAP, biocompatible, natural polymer chitosan and antibiotic gentamicin were employed. The obtained composite hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) was assembled on pure Ti plates using the cathodic electrophoretic deposition process from an aqueous suspension. The aim was to produce a uniform bioactive coating with improved mechanical strength and favorable antibacterial properties. HAP/CS/Gent coatings were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FE-SEM). Addition of the polymer significantly improved morphology, and bioactivity of thus formed composite. HAP/CS/Gent composite coatings exhibited strong antibacterial activity against Staphylococcus aureus and Escherichia coli.", publisher = "Novi Sad : University of Novi Sad, Faculty of Technology", journal = "12th Conference for Young Scientists in Ceramics, CYSC-2017", title = "Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin", pages = "93-93" }
Stevanović, M., Đošić, M., Janković, A.,& Mišković-Stanković, V.. (2017). Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin. in 12th Conference for Young Scientists in Ceramics, CYSC-2017 Novi Sad : University of Novi Sad, Faculty of Technology., 93-93.
Stevanović M, Đošić M, Janković A, Mišković-Stanković V. Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin. in 12th Conference for Young Scientists in Ceramics, CYSC-2017. 2017;:93-93..
Stevanović, Milena, Đošić, Marija, Janković, Ana, Mišković-Stanković, Vesna, "Electrophoretically deposited bioactive hydroxyapatite/chitosan coatings loaded with gentamicin" in 12th Conference for Young Scientists in Ceramics, CYSC-2017 (2017):93-93.